Fall 2005 syllabus for Biochemistry I (CHEM 4400).  

What is the most abundant protein in your body? 

 Instructions for the Writing Assignment.

Office hours: T: 9-10, TWRF: 11:20-12:20

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Chapter 1:  Scavenger Hunt Questions.

Chapter 2: Water topics, pH calculations, bicarbonate problems.  You may want to revisit the Buffer lab for CHEM 1110.  Also, check out the problems on Dr. Booker's Penn State Biochemistry page.  

Chapter 3:  Titration of an amino acid.  Also, start memorizing the structures, names, three letter and one letter codes for the amino acids.  Also, you will need to know the pKa values for the amino acids that have ionizable side chains.  (See the "Exercises" section for some useful links.) 

Chapter 4: Collagen Diseases. 

Be sure to check this area often.

Homework

• Chapter 1: 1-11, see if you can figure out the mistake in #12, 13.  Many of these problems help you refresh your analytical thinking skills.  You need to you dimensional analysis for several of them.  Getting the correct answer is good, knowing how to solve problems is the primary goal of these exercises.
• Chapter 2: 1-16
• Chapter 3: 1-5,7-13,15-18  
• Chapter 4: 1-10  You will need to go to http://www.ebi.ac.uk/InterProScan/ and type in part (~30 aa) of the protein sequence for #10.What is the most abundant protein in your body?  Goodpasture's Disease
• Chapter 5: 1-10, 12, 13  The living graphs for #13 are on the CD that accompanied your book.
• Chapter 6: 3-19
• Chapter 7: 5,6,8-10,12,14
• Chapter 10: 1-8,10,11,12,13
• Chapter 11: 1,2,3-11

Supplementary Materials:

• What is the most abundant protein in your body? 
• There are two types of T_H cells!
• B cell immunity by Professor Schlissel at UCBerkeley
• Molecular Immunology lectures at UCB
• Cool pictures of Macrophages!  
• More info about fats: lipases, Tay Sach's disease, and Nieman Pick disease.
• Some more information about enzymes: What are thermodynamics? What are kinetics?
• Link to Ceruloplasmin Function, now that is a multi-tasking enzyme! 
• Link to Wilson's disease: Ceruloplasmin levels are linked to liver function.
• Commonly used liver tests
• Kids and Chemistry: this American Chemical Society page has ideas for activities you can do with kids.

Please let Dr. Stone know your opinion!  Take a few moments to complete this anonymous survey. 

Exercises

• More practice problems that are based on our text can be found Dr. Booker's Biochemistry page.
• The one letter codes for the amino acids are in a table on page 118 in Lehninger Principles of Biochemistry by Nelson and Cox. Also, you can check out the previous quiz on the amino acids.
• Practice pI problems: amino acids or polypeptides
• Here is some more information about Myoglobin and Hemoglobin . There is also extra information about Hill plots and cooperative binding.
• Practice problems that relate to enzymes , and here are the answers!

Sing these words to the tune from a favorite jingle for canned food:

When it says
"Lipids, lipids, lipids
on the label, label, label,
you will like it, like it, like it,
on your table, table, table"

Now go to the list of common fatty acids that you need to memorize. You need to know the common name, the short hand notation and the structures .

• Questions for Membrane Transport
• An Adventure in DNA Structures

Old Exams

Exam I 2002

Exam II 2002, Exam II 2003

Exam III 2002, Exam III 2004

Exam IV 2002

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Biochemistry related sites

An electronic overview of biochemistry , written by Dr. William McClure, Department of Biological Sciences, Carnegie Mellon University, Pittsburgh, PA 15213

University of Kansas Medical Center's Medical Biochemistry site. This is what you have to look forward to learning! Be sure to check out their practice exams. There are some intriguing questions on them!


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Created by Koni Stone, koni@chem.csustan.edu
Last edited August 29, 2004