| Office: 213 Science, 667-3570, koni@chem.csustan.edu |
Office hours: T: 9-10 T, W, R, F: 11:20-12:20 |
Text: Lehninger Principles of Biochemistry by David Nelson and Michael Cox, 4th Edition, Worth Publishers, 2004. |
Web page for the class: http://wwwchem.csustan.edu/chem4400/4400main.htm
Welcome to the first semester of a full year course in Biochemistry.
You
must have taken and passed (a C or better is highly recommended) 2
semesters
of Organic chemistry in order to enroll in this course.
The learning goals for this class are:
1. Learn biochemical facts, including the language used to describe
biochemistry and the methods used to study it.
2. Gain an understanding of some biochemical principles including
| Device | Dates | Points | Percent of total points |
| Exams | September 30, October 28th, and December 2. There are no make-up exams, please plan accordingly. | 300 |
37.5 |
| Quizzes, Assignments and Activities | Any day except exam days (actual points will be normalized to 100 points) | 100 |
12.5 |
| Service learning | Final report due December 2, 2005 | 100 |
12.5 |
| Comprehensive Final Exam | Friday, December 16, 2005, 8:30-10:30 |
200 |
25 |
| Literature reports |
Due dates: September 30 (Brief summary 10 points) October 31 (1st draft 30 points) November 28 (Final draft 60 points) |
100 |
12.5 |
This course is graded with letter grades using the following
minimum scores:
A, 90%; B, 80%; C, 70%; D, 60%.
The last day to withdraw from this course is Tuesday, October 4, 2005.
The final exam will be comprehensive and will be based on questions that were on the quizzes, activities and exams.
Service based learning is a great way to gain a greater understanding of chemistry while having fun. You can choose from several options in order to fulfill this course requirement.
After you have completed your service based learning activity, you will need to complete a written report. Please include the following:
Literature
summaries For each of three writing assignments, select a paper
that is
published in one of the journals selected for this course (See list.) Your article must have methods, data and
results
sections. It is best to avoid papers with humans or extensive
animal
studies. Those papers usually involve a myriad of statistical
methods
that we will not be able to comprehend.
First, write a brief summary of your article. What is significant about these results? Why is this paper interesting? What disease is related to these results? Who did the work? Where are they located? This assignment is worth 10 points and it is due September 30th.
Then, for the first (30 points, due October 31) and final drafts (60 points, due November 28) of your literature analysis, include the following in your written report:
1. Briefly explain the rationale and
significance of the work in this paper. Why is this paper
interesting? What does this paper
contribute to the understanding of the topic? Your audience is your
classmates, you will need to define terms and explain concepts that
have not been covered in General, Organic or this first semester of
Biochemistry. You will have to consult other books and journal
articles
to do this well.
2. Briefly describe the techniques that were used. What
experiments
were done? Leave out the details (no volumes, temperatures or reaction
times.)
3. Analyze the data and the results.
What do the results of the experiments mean? Draw some
conclusions from
your analysis.
4. Compare your analysis of the results
with the authors' conclusions. Also, search the literature for
similar
studies and compare those results with the results in your paper.
5. Be sure to cite all of your sources in a well documented
bibliography that includes all authors, titles, pages and dates of
publication.
These reports must be generated using a word processing computer program. No handwritten text, tables or graphics will be accepted. Please use double spacing and select a font that has 10-12 characters per inch. Both MacIntosh and IBM machines are available for your use in the computer labs in the Library building. If you are in need of assistance, it is your responsibility to schedule a computer lesson with me.
Homework: Problems from the text will be assigned and some problems will be presented in class by students. Please consult the main page for this class.
| Week | Chapter |
| 1 |
1: Intro,Cells, Biomolecules
|
| 2 |
2: Water
|
|
3 |
3: Amino acids, peptides and proteins
|
| 4 |
4: 3D Protein structure
|
| 5 | 5: Protein function |
| 6 | 6: Enzymes |
| 7 | 6: Enzymes |
| 8 | 7: Carbohydrates and glycobiology |
| 9 | 8: Nucleotides and nucleic acids |
| 10 | 9: DNA based information technologies |
| 11 | 10: Lipids |
| 12 | 11: Biological membranes and transport |
*Other supplemental reading material may be assigned
Note: This syllabus is intended to be used as a guide, it is not a legal contract.